Son of John W. Wilkerson and Rebecca H. Kilgore. He had 4 children from his first marriage: Julia Ann Wilkerson, John W. Wilkerson Jr., Thomas H. Wilkerson and Rebecca A. Wilkerson. He remarried to Melinda Hathcock on 12th March 1883. They had 6 children: Samuel Matthew Wilkerson, John Isaiah Wilkerson, Malinda D. Wilkerson, Jackson Wilkerson, Frances Teria Wilkerson and Luther M. Willkerson.
23671900 Census of Oneonta, Blount Co AL
Household Members Age RelationshipJohn W Wilkerson 39 Head
Malinda Wilkerson 42 Wife
Rebecca Wilkerson 16 Daughter
Samuel M Wilkerson 15 Son
James I Wilkerson 13 Son
Malinda D Wilkerson 11 Daughter
Jackson C Wilkerson 6 Son
Luther M Wilkerson 2 Son
John R Hathcock 26 Brother in Law
Lee Lowe 25 Nephew